Importance of immediate surgical intervention and antifungal treatment for rhinocerebral mucormycosis: a case report
김진근, 박혜정, 박중현, 백지웅, 김형준, 차인호, 남웅,
소속 상세정보
김진근 ( Kim Jin-Geun ) - Yonsei University College of Dentistry Department of Oral and Maxillofacial Surgery
박혜정 ( Park Hye-Jeong ) - Yonsei University College of Dentistry Department of Oral and Maxillofacial Surgery
박중현 ( Park Jung-Hyun ) - Yonsei University College of Dentistry Department of Oral and Maxillofacial Surgery
백지웅 ( Baek Ji-Woong ) - Yonsei University College of Dentistry Department of Oral and Maxillofacial Surgery
김형준 ( Kim Hyung-Jun ) - Yonsei University College of Dentistry Department of Oral and Maxillofacial Surgery
차인호 ( Cha In-Ho ) - Yonsei University College of Dentistry Department of Oral and Maxillofacial Surgery
남웅 ( Nam Woong ) - Yonsei University College of Dentistry Department of Oral and Maxillofacial Surgery
KMID : 0355620130390050246
Abstract
Rhinocerebral mucormycosis (RCM) is an opportunistic, potentially life-threatening fungal disease. This infective disease invades not only the facial sinuses, but also the maxilla, zygoma, and rhino-cerebral structures with a massive destruction of the facial skeletons and soft tissue. This disease progresses within various underlying diseases, such as diabetes mellitus, hematologic malignancy, renal failure, and systemic immunodepression. The relationship between mucormycosis and these underlying conditions have been discussed extensively in the literature. The authors studied 6 cases of RCM diagnosed by a tissue biopsy and treated at the department of oral and maxillofacial surgery, from 1997 to 2012. Patients were treated with several kinds of surgical interventions and antifungal agents, and their clinical & radiological signs, underlying conditions, surgical methods, and outcomes were analyzed.
키워드
Mucormycosis; Diabetes mellitus; Diagnosis
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